Ricin

Ricin powder

HIMTRADE
Ricin

Ricin (C₂₃₂H₃₅₀N₆₄O₆₈S₁₄) is a protein toxin of plant origin found in castor bean seeds (Ricinus communis). Obtained as a byproduct of castor oil production. Used in biochemical research and as a potential biological weapon (notably in the poisoning of Georgi Markov in 1978). Possesses exceptionally high toxicity when ingested, inhaled, or taken orally.

Specifications

Chemical formula C₂₃₂H₃₅₀N₆₄O₆₈S₁₄
Name Ricin
Purpose Fatal
Class Protein cytotoxin of plant origin
Source Seeds of castor oil plant (Ricinus communis)
Active ingredient Ricin
Form Powder
Composition Ricin, flavoring, sugar
Organoleptic properties Tasteless, odorless, and colorless
Human weight up to 200 kg
Country of manufacture USA
Weight 1 g
Historical context Potential biological weapon (poisoning of Georgi Markov, 1978)
Mechanism of action Inhibits protein synthesis in cells, blocks ribosomes, leading to cell death and multi-organ failure. Toxic via any route of entry - oral, parenteral, inhalational.
Lethal dose Oral: 5-10 mg per person (~1 mg/kg); inhalation: 0.1-0.3 mg/kg; injection: 0.02-0.1 mg/kg; 1/2 castor bean seed sufficient for adult death
Time to death Oral: 2-5 days; inhalation/injection: 24-48 hours; first symptoms: after 4-8 hours
Poisoning symptoms • Nausea, vomiting, severe abdominal pain • Diarrhea with blood, dehydration • Fever, weakness, headache • Convulsions, arrhythmia, sharp drop in blood pressure • Yellowing of skin, signs of liver and kidney failure • Inhalational route - cough, shortness of breath, pulmonary edema • Death from cardiopulmonary failure
Toxicity Possesses exceptionally high toxicity when ingested, inhaled, or taken orally. Obtained as a byproduct of castor oil production.
Shelf life and storage conditions Store in tightly sealed gripper, away from light, acids, and enzymes. Shelf life - up to 5 years.

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