Batrachotoxin
Batrachotoxin crystals for suicide
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Batrachotoxin (C₃₁H₄₂N₂O₆) is one of the most potent non-protein poisons of natural origin. Extracted from the skin and feathers of South American frogs of the genus Phyllobates and some birds of New Guinea. Not used in medicine or industry due to extreme toxicity. Studied in neurophysiology in small doses as a sodium channel blocker. It is an extremely powerful neurotoxin with no known antidote.
Specifications
| Chemical formula | C₃₁H₄₂N₂O₆ |
|---|---|
| Name | Batrachotoxin |
| Purpose | Fatal |
| Class | Alkaloid neurotoxin |
| Source | Skin and feathers of Phyllobates frogs (South America), New Guinea birds |
| Active ingredient | Batrachotoxin |
| Form | Small crystals |
| Composition | Batrachotoxin, flavoring, food additives |
| Human weight | up to 170 kg |
| Substance quantity | 1 g |
| Country of manufacture | India |
| Weight | Total with bottle 80 g |
| Lethal dose | 0.002-0.01 mg/kg (less than 100 mcg can be fatal) |
| Time to death | Parenteral: 1-3 minutes; skin absorption: up to 30 minutes |
| Mechanism of action | Disrupts voltage-gated sodium channels, causing irreversible depolarization of cell membranes and muscle paralysis. Affects heart and respiratory muscles. Dozens of times more potent than curare and cyanides. |
| Poisoning symptoms | • Burning and numbness at contact site • Muscle weakness, loss of coordination • Convulsions, cardiac arrhythmia • Drop in blood pressure, paralysis of respiratory muscles • Death while conscious due to asphyxia |
| Toxicity | One of the most potent non-protein poisons. No antidote exists. Effective through parenteral administration and via damaged skin/mucous membranes. Death occurs from respiratory arrest and ventricular fibrillation. |
| Shelf life and storage conditions | Store in airtight glass bottle. Avoid contact with air and light. Shelf life - up to 2 years. |
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